The Malek Lab at the University of Miami Miller School of Medicine is recruiting Postdoctoral fellows to study the cellular and molecular mechanisms contributing to regulatory T cell-based immunotherapy of autoimmune diseases, with a focus on type 1 diabetes. Current projects offer the opportunity to participate in highly translational and collaborative effort aimed at re-regulating immune responses to restore tolerance by selectively boosting regulatory T cells through the application of limiting amounts of IL-2 or novel IL-2 analogs with improved pharmacology. Our efforts encompass mechanistic studies on how low dose IL-2 acts on human Treg and T effector cells. Underpinning this effort is a new phase 2 multi-center clinical trial in type 1 diabetes organized at the University of Miami. Mouse models are also used to further define the activity of such pathways in vivo.
The minimum qualifications for this position are as follows: Prior experience in immunology, including mouse models of autoimmune disease, human immunology, flow cytometry, tissue imaging and/or in molecular biology and bioinformatics is preferred. Highly motivated individuals with a recent Ph.D., a strong track record of research as evidenced by publications in peer reviewed journals, and excellent communication skills are encouraged to apply.
Please send a cover letter that includes why you are interested in this position, a curriculum vitae and names of three references by email in PDF format to:
Dr. Thomas Malek
Professor and Interim Chair
Department of Microbiology and Immunology
University of Miami Miller School of Medicine
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